Read the information and view the graphics. Use this information to answer the following questions:
1. Describe the primary structure of collagen. What are the major amino acid components?
1. Describe the primary structure of collagen. What are the major amino acid components?
The major amino acids are glycine, proline, and hydroxyproline. Triple Helix is a type of collagen and is a long rope-like structrure. They are braided together by three polypeptide chains. Every 3rd amino acid(glycine) is perfectly fitted into the helix. The rest are filled into the helix which is proline and hdroxyproline.
2. What role does vitamin C play in collagen formation? What happens when a person does not get enough vitamin C in his or her diet?
Vitamin C helps create hydroxyproline so it is very important to have it. The body cannot produce vitamin C sooo we have to make sure we have it in our foods or diet. When we don't the production of collagen slows down, this can cause scurvy.
3. Describe the quaternary structure of collagen (the way in which the polypeptide chains are arranged).
Like braiding your hair, that is how collagens are structured. They come together making long strands side by side. They unite with the heads connecting and the tails far away apart.
1. What is the main symptom of osteogenesis imperfecta? What are some other symptoms that people with OI may have?
Some symptoms are that you are very fragile and bones can break or fracture. The loss of hearing can start and joint laxity. Also, curved bones( scoliosis) and having short stature. Those are some symptoms of OI.
2. Type I osteogenesis imperfecta causes fewer problems than the other forms. How does the collagen structure in Type I OI differ from that of the other types?
The collagen structrue is very normal which makes it different then ever other collagen. Except you don't have an average amount, you have less.
2. What role does vitamin C play in collagen formation? What happens when a person does not get enough vitamin C in his or her diet?
Vitamin C helps create hydroxyproline so it is very important to have it. The body cannot produce vitamin C sooo we have to make sure we have it in our foods or diet. When we don't the production of collagen slows down, this can cause scurvy.
3. Describe the quaternary structure of collagen (the way in which the polypeptide chains are arranged).
Like braiding your hair, that is how collagens are structured. They come together making long strands side by side. They unite with the heads connecting and the tails far away apart.
1. What is the main symptom of osteogenesis imperfecta? What are some other symptoms that people with OI may have?
Some symptoms are that you are very fragile and bones can break or fracture. The loss of hearing can start and joint laxity. Also, curved bones( scoliosis) and having short stature. Those are some symptoms of OI.
2. Type I osteogenesis imperfecta causes fewer problems than the other forms. How does the collagen structure in Type I OI differ from that of the other types?
The collagen structrue is very normal which makes it different then ever other collagen. Except you don't have an average amount, you have less.
1. Describe the role of collagen in bones. Why do collagen problems lead to bone problems?
Collagen is like the foundation of your bones, making them stronger! Bones have a frame and collagen builds on them making them not as fragile or easy to break.
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